Different drugs have different effects (obviously…) and
abusing them can cause serious damage to yourself (they can interfere with your
neural pathways, cause addiction etc). One of the main ways it does this is by
interfering with the neurons in your brain by binding to neuron receptors. They
can then mimic the effect of different neurotransmitters (chemical messengers)
and make these receptors under- or over-sensitive to neurotransmitters and this
has a major impact on your brain and how it functions. (For more detail on this
process, check out this Scientific American article). They can also change the
structure of your brain, depending on what drug you abuse. But what they do not
do is create actual holes in your brain. The only thing that can create holes
is physical trauma.
Sources:
http://science.howstuffworks.com/life/inside-the-mind/human-brain/10-brain-myths.htm#page=2
Sources:
http://science.howstuffworks.com/life/inside-the-mind/human-brain/10-brain-myths.htm#page=2
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